Ukwelashwa kwe-MCAS, ukuphathwa kwe-mast cell activation syndrome, i-H1 antihistamine, i-H2 blocker, i-cromolyn sodium, i-ketotifen, i-leukotriene inhibitor, uhlelo oluphuthumayo lwe-MCAS, i-epinephrine anaphylaxis, imithi ye-MCAS

Indlela ehlakaniphile - ama-antihistamine e-H1 kanye ne-H2, ama-stabilizer, ama-leukotriene inhibitors - kanye nokunciphisa i-trigger, ukuhlela izimo eziphuthumayo kanye nemigomo engokoqobo.

Ukwelashwa kwe-MCAS | Imininingwane ye-MCAS

Izinsiza - Ukwelashwa
Skrola
Isekelwe Ebufakazini
Abaphathi
Alikho ikhambi le-MCAS. Nokho, kunendlela esungulwe kahle enezinyathelo eziletha izimpawu ngaphansi kokulawulwa okunengqondo kwenani elikhulu leziguli.
Qala Ukufunda Finyelela Izinsiza
0
izigaba ezibanzi ku
stepwise indlela
0
izinhlobo ze-histamine receptor
kuvame ukuvinjwa ndawonye
0amasonto
ubude besilingo obujwayelekile ngaphambili
ukwahlulela umuthi

0

ushintsho ngesikhathi - umthetho
lokho kwenza izilingo zifundeke

Umshwana wokuzikhipha emthwalweni wezempilo: Leli khasi liyafundisa futhi alisona iseluleko sezokwelapha. I-MCAS yethula ngendlela ehlukile kuso sonke isiguli - hlala usebenza nabahlinzeki bezempilo abaqeqeshiwe abawazi umlando wakho ngaphambi kokuthatha isinyathelo kunoma yini oyifunda lapha.

Uhlaka

Indlela Ukwelashwa
Ingabe Isondele

Ukuphatha kwakhelwe phezu kwezinsika ezimbili - ukunciphisa lokho okucasula ama-mast cells, kanye nokuzinza ukuthi asabela kanjani kalula. Ayikho enye esebenza kahle ngaphandle komunye.

Isimiso esibusayo siwukukhuphuka kancane kancane. Ukwelashwa ngokuvamile kuqala ngezinketho ezinqunyiwe neziphansi kakhulu zobungozi, kugcina ngakunye isikhathi eside ngokwanele ukwahlulela ngokwethembeka, futhi kwengeze amanye ama-ejenti kuphela lapho kudingeka. Ukuqala imishanguzo eminingana ngasikhathi sinye kulinga lapho izimpawu zizimbi, kodwa kwenza umphumela ungachazeki - uma izinto ziba ngcono, akekho owaziyo ukuthi yiluphi ushintsho olube nesibopho, futhi uma okuthile kubangela ukusabela, akekho owaziyo ukuthi yini okufanele ayiyeke.

Umgomo wesibili ukuthi izilingo zidinga isikhathi. Izinzinzisi ze-mast cell ikakhulukazi zingathatha amasonto ukukhombisa umphumela wazo ogcwele, futhi ukuzishiya kusenesikhathi kuyindlela evamile yokulahla okuthile obekungasebenza. Ukuhlolwa okungamaviki amane kuya kwayisithupha ngoshintsho kuyisimiso esivame ukucashunwa, nakuba isikhathi esifanele sihluka ngokwe-ejenti kanye nokwahlulela kodokotela.

Okwesithathu ukuthi izithako ezingasebenzi zibalulekile. Odayi, izihlungi, nezivimbelakuvunda ekwakhekeni kungavusa ukusabela ngaphandle komuthi osebenzayo, ngakho isiguli singase sibekezelele inguqulo yomkhiqizi oyedwa futhi sisabele komunye. Lapho lokhu kusolwa khona, ngezinye izikhathi kusetshenziswa amalungiselelo ahlanganisiwe.

Okokugcina, okuhlosiwe kuwumsebenzi esikhundleni sokuphelela. Ukuqedwa ngokuphelele kwezimpawu akuwona umgomo ongokoqobo weziguli eziningi. Ukwehliswa okunenjongo kwemvamisa nokuqina - okwanele ukubuyisela umsebenzi, imfundo, kanye nempilo yomphakathi - kunjalo.

Indlela ye-Stepwise

Imithi Izigaba

Isigaba sokuqala - ama-antihistamine e-H1. Izivimbeli ze-H1 zesizukulwane sesibili ziyisiqalo esijwayelekile, esikhethelwa iphrofayili yomphumela ongathandeki. Babhekana nezimpawu eziqhutshwa yi-histamine iziguli eziningi ezizibona kuqala: ukulunywa, ukushaywa umoya, ukuqunjelwa, i-rhinitis. Abanye odokotela basebenzisa imithamo engaphezu kwesilinganiso sokungezwani komzimba esivamile esifweni se-mast cell, okuyisinqumo somuntu onikezwe imithi esikhundleni sendaba yokuzilungisa.

Isigaba sesibili - ukwengeza ama-antihistamine e-H2. I-histamine isebenza ohlotsheni olungaphezu kolulodwa lwama-receptor, futhi ama-H2 receptors agxile emgudwini wamathumbu. Ukuvimba i-H1 ne-H2 ndawonye kuvame ukukhiqiza ukulawula okungcono kunokwedwa, ikakhulukazi ku-reflux, isicanucanu, kanye nezimpawu zesisu ezishiywa ama-H1 engakathintwa.

Isigaba sesithathu - ama-mast cell stabilizers. Esikhundleni sokuvimbela umphumela wabalamuli abakhululiwe, lezi zihlose ukunciphisa ukukhululwa kwasekuqaleni. I-Cromolyn sodium ne-ketotifen yizinto ezisetshenziswa kakhulu. Ayanensa ekusebenzeni, adinga amasonto okusetshenziswa okungashintshi ngaphambi kokuba inzuzo ibonakale, futhi i-cromolyn esesimweni somlomo isebenza ikakhulukazi emathunjini.

Isigaba sesine - ama-leukotriene inhibitors nama-ejenti engeziwe. Ngenxa yokuthi ama-leukotrienes anesandla ezimpawu zokuphefumula nezamathumbu ezingafinyeleli ama-antihistamine, abaphikisi be-leukotriene receptor bavame ukungezwa. Ngale kwaleli phuzu, abaphathi baya endaweni ehluka kakhulu ngesiguli kanye nochwepheshe, okuhlanganisa i-aspirin ye-prostaglandin-mediated flushing ezigulini ezikhethiwe, kanye nokwelashwa kwe-biologic njenge-omalizumab ezimweni eziphikisayo. Lezi zithwala ubungozi obuzwakalayo kanye nokuphikisana okuthile futhi zihambisana ngokuqinile nochwepheshe.

Wonke umenzeli oshiwo lapha unikezwa njengokuqondiswa kwendlela eshicilelwe - hhayi njengesincomo. Umthamo, ukulandelana, ukusebenzisana, nokufaneleka kuncike emlandweni womuntu ngamunye, kanye nezinqumo zokunquma ezikadokotela wakho.

  • I-Stepwise Logic
  • Kungani I-oda
    Izindaba
  • Isigaba ngasinye sikhuluma nabalamuli leso sangaphambili sishiya singaphathwanga. Ukwenyuka ngokulandelana kugcina isithombe sitolika.
  • I-H1 antihistamines - isikhumba futhi upper airway - ukulunywa, flushing, isifuba, rhinitis
  • I-H2 antihistamines - imiphumela ye-histamine yamathumbu - i-reflux, isicanucanu, i-cramping
  • Iziqinisi zeseli ye-Mast - ukunciphisa ukukhululwa kunomphumela wokuvimba; ephuza ukubamba
I-Leukotriene inhibitors - Izimpawu zokuphefumula kanye ne-GI ama-antihistamine awafaki

Ama-ejenti angochwepheshe - i-aspirin, i-biologics nabanye - amacala akhethiwe, ukunakekelwa kochwepheshe

Ushintsho olulodwa ngesikhathi - umthetho owenza noma yikuphi kwalokhu okungenhla kuchazeke

Ngaphandle Kwemithi

Qalisa Ukunciphisa
& Ukuphathwa Kwansuku zonke

Iziguli zivame ukubika ukuthi ukwehlisa inani le-trigger load kuzenzela okuningi njenganoma yimuphi umuthi owodwa. Zombili zisebenza ndawonye - ukulawulwa kwemithi kuphakamisa umkhawulo, ukunciphisa i-trigger kugcina umthwalo wansuku zonke ngaphansi kwakho.

Umgomo wokupakisha kusuka Izicupha isebenza ngqo lapha. Ngoba ukwenza kusebenze kukhombisa umthwalo okhulayo, ukususa ngisho nokucasula okumbalwa okuthembekile kungakha i-headroom eyanele ukuthi ukuchayeka okuvamile kuyeke ukubangela ukusabela. Lokhu kuvame ukuvela lapho izinzuzo zakuqala eziphawuleka kakhulu.

Izinyathelo ezisebenzayo ezivelayo kuma-akhawunti esiguli zihlanganisa ukugcina izinga lokushisa lendawo lizinzile, ukukhetha imikhiqizo engenamakha, ukubeka kuqala ukudla okusha kunokudla okudala noma okugcinwa isikhathi eside, ukuvikela ukulala, nokwakha umsebenzi womzimba kancane kancane kunokuwuyeka. Akukho kulokhu okumangalisayo ngokwako; ndawonye bashintsha isisekelo.

Ukuphathwa kokudla kufanele kuqashelwe ngokukhethekile. Ukudla okune-histamine ephansi kuvame ukuzama, kodwa ubufakazi obusekelayo bunomkhawulo futhi umkhawulo ubalulekile. Ukuqedwa isikhathi eside okungagadiwe kunengozi yangempela yokuntuleka kokudla okunomsoco kanye nokudla okungenamsoco, futhi leyo ngozi iphezulu entsheni. Uhlolo oluhlelekile, olunomkhawulo wesikhathi nokwethulwa kabusha okuhlelekile - ngokufanelekile ngokubandakanyeka kwabadlayo - kuyindlela ephephile.

Umshwana wokuzikhipha emthwalweni wezempilo: Leli khasi liyafundisa futhi alisona iseluleko sezokwelapha. I-MCAS yethula ngendlela ehlukile kuso sonke isiguli - hlala usebenza nabahlinzeki bezempilo abaqeqeshiwe abawazi umlando wakho ngaphambi kokuthatha isinyathelo kunoma yini oyifunda lapha.

Kuyafaneleka ukuqamba igama lesicupho ngokuqondile: kungenzeka ukunciphisa izimbangela ngobudlova kangangokuthi ukuphila kuvumelana cishe lutho. Uhlelo oluqeda ukusabela ngokuqeda umsebenzi, isikole, izinhlobonhlobo zokudla, nokuxhumana nabantu luye lwahweba uhlobo oluthile lokulimaza lwaba olunye. Umgomo impilo ebanzi kunazo zonke ezosekelwa yi-physiology yakho, hhayi impilo encane egwema izimpawu.

Ukuphepha

Isimo esiphuthumayo Ukuhlela

Ezinye iziguli ezinesifo se-mast cell zisengozini ye-anaphylaxis - ukusabela okusheshayo, okunzima, okungase kube yingozi empilweni. Lapho lobo bungozi busebenza khona, ukuyihlela akuyona into ozikhethela yona, futhi kuyingxoxo ongaba nayo nodokotela wakho ngaphambi kokuba idingeke kunangesikhathi.

Iziguli ezibhekwa njengezisengozini ngokuvamile zinikezwa ama-epinephrine auto-injection futhi ziyalelwa ukuthi ziwathwale njalo. I-epinephrine iwumugqa wokuqala wokwelapha we-anaphylaxis; ama-antihistamine awathathi indawo yawo futhi akufanele kuthenjelwe kuwo ekuphenduleni okunzima kakhulu.

Uhlelo olubhaliwe lwesenzo esiphuthumayo, okuvunyelenwe ngalo nodokotela wakho, luwumkhuba ojwayelekile. Kufanele ibeke izimpawu eziyisixwayiso ezibonakalayo, ukuthi iphathe ini futhi nini, futhi nini lapho kufanele ishayele abezimo eziphuthumayo. Amakhophi anikezwe umndeni, ozakwenu, noma abasebenzi besikole asho ukuthi abantu abaseduze nawe bangakwazi ukwenza okuthile uma ungakwazi.

Umazisi wezokwelapha - isongo noma ikhadi eliphawula ukuxilongwa kwe-mast cell kanye nanoma yiziphi izimbangela zomuthi ezaziwayo - kutuswa kakhulu, njengoba abasebenzi bezimo eziphuthumayo bangase bangasazi isimo noma ama-ejenti angenza ukusabela kubi nakakhulu.

Lesi sigaba sichaza okuvamile futhi asikwazi ukumiselela uhlelo olwakhelwe emlandweni wakho. Uma ungazange uxoxe nodokotela wakho ngokuhlela izimo eziphuthumayo, leyo ngxoxo kufanelekile ukuyicela ngesikhathi sakho esilandelayo.

I-Outlook

Iyiphi Intuthuko
Empeleni Kubukeka sengathi

I-MCAS yisimo esingelapheki futhi ukuphathwa kwamanje kuwuphawu kunokwelapha. Ukubeka okulindelwe ngokwethembeka ekuqaleni kwenza inqubo ibe lula kakhulu ukuyigcina.

Ukuthuthukiswa kuvame ukuhamba kancane futhi akunamugqa. Ukuvutha kusengenzeka, ngokuvamile ngesikhathi sokutheleleka, izikhathi zokucindezeleka, noma ukushintsha kwamahomoni, futhi ukuvutha akusho ukuthi ukwelashwa kwehlulekile. Okubalulekile ukuthambekela kuzo zonke izinyanga kunesimo sanoma yiliphi iviki.

Awuyena Ngedwa

Imininingwane ye-MCAS ikhona ukuze kuqinisekiswe ukuthi sonke isiguli siyakwazi ukuthola ukwesekwa, umphakathi, kanye nolwazi lokuzikhulumela. Joyina inethiwekhi yethu yomhlaba wonke.

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