Izinto ezibangelayo azifane zibe ngumoni omnye. Ziyaqokelela - yiyo loo nto isidlo esifanayo, igumbi elinye, okanye ukuhamba okufanayo kunokuba yingozi ngenye imini kwaye kungenakunyamezeleka okulandelayo.
Olona luvo luluncedo kakhulu lokulawula i-MCAS kukuba ukuvuselela kuyaqokelelwa. Iiseli zeMast ziphendula kumthwalo opheleleyo, hayi kwinto enye kuluhlu.
Olona luvo luluncedo kakhulu lokulawula i-MCAS kukuba ukuvuselela kuyaqokelelwa. Iiseli zeMast ziphendula kumthwalo opheleleyo, hayi kwinto enye kuluhlu.
Izigulane zidla ngokuchaza indlela abasabela ngayo njengento engalindelekanga. Ukuhlolwa okukufutshane kudla ngokubonisa into enocwangco ngakumbi: ukutyhileka okuliqela okunyamezelekayo okufika kufutshane ngokwaneleyo ukuba kunqumle umda ekungekho namnye ubenokuwuwela yedwa. Igumbi elishushu liyalawuleka. Iglasi yewayini ebomvu iyalawuleka. Iveki enoxinzelelo iyalawuleka. Bobathathu ngobusuku obunye abanjalo.
Iipropathi ezimbini ezizezinye zenza ukuba kube nzima ukucinezela izitshizi. Iimpendulo zinokuba njalo ilibazisekile, ezibonakala iiyure emva kokuba sesichengeni kunokuba ngokukhawuleza, nto leyo eqhawula ikhonkco elibonakalayo phakathi konobangela nesiphumo. Kwaye iseti yokuqalisa umntu ngamnye utshintsho ngokuhamba kwexesha, ukwanda ngamaxesha olawulo olulambathayo kwaye kaninzi ukucutheka kwakhona xa unyango luzisa ukusebenza kwakhona kwesiseko phantsi.
Intsingiselo esebenzayo yeyokuba ukuchongwa kwe-trigger kumalunga neepateni kunesehlo esinye. Into etyhila isiqalo yirekhodi egcinwe kwiiveki, hayi isiphelo esithathwe kwimvakwemini embi.
Intsingiselo esebenzayo yeyokuba ukuchongwa kwe-trigger kumalunga neepateni kunesehlo esinye. Into etyhila isiqalo yirekhodi egcinwe kwiiveki, hayi isiphelo esithathwe kwimvakwemini embi.
Izinto ezibangela umzimba lolona didi ludla ngokuphoswa, kuba alubandakanyi nto ingena emzimbeni kwaphela. Iiseli zeMast ziphendula ngokuthe ngqo kumatshini kunye ne-thermal stimuli-yiyo loo nto uvavanyo oluqhelekileyo lokwaliwa, olwakhelwe malunga nokuchonga iiproteni, alufumani nto.
Ubushushu iphakathi kwezona zixelwa rhoqo. Ubushushu, ukubanda, kunye notshintsho olukhawulezileyo phakathi kwazo zonke zinokuvuselela ukusebenza. Iishawa ezishushu, ii-saunas, ukutshintsha kwemozulu ngesiquphe, kunye nokuhamba phakathi kwe-air conditioning kunye nomoya wasehlotyeni ziiakhawunti eziqhelekileyo.
Ubushushu iphakathi kwezona zixelwa rhoqo. Ubushushu, ukubanda, kunye notshintsho olukhawulezileyo phakathi kwazo zonke zinokuvuselela ukusebenza. Iishawa ezishushu, ii-saunas, ukutshintsha kwemozulu ngesiquphe, kunye nokuhamba phakathi kwe-air conditioning kunye nomoya wasehlotyeni ziiakhawunti eziqhelekileyo.
Uxinzelelo kunye nengxabano eluswini unokuvelisa ukusabela okubonakalayo. I-Dermographism - apho ukuphulula ngokuqinileyo ulusu kuphakamisa i-welt ecaleni komgca woqhagamshelwano - luphawu olwaziwayo, kunye nempahla eqinileyo, amabhanti esinqeni, kunye neentambo zamagxa zinokwanela.
Amavumba kunye neekhemikhali ezihamba emoyeni - ivumba, iimveliso zokucoca, umsi, ipeyinti entsha, ikhaphethi entsha - zixelwa rhoqo ngokwaneleyo ukuba indawo ezingenavumba zisisicelo esiqhelekileyo sokuhlala. Ukungcangcazela kwaye ukukhanya kwelanga azixhaphakanga kodwa zibhalwe.
Ezi zisebenza kwiiseli zemast ngoomatshini okanye ngobushushu. Iiphaneli eziqhelekileyo zokwaliwa aziyilwanga ukuba zichonge nayiphi na kuzo.
Izinto ezibangela ukutya kwi-MCAS zihlala zimalunga nomxholo we-histamine kunye nokucaphuka kweeseli zemast kunokuba kukwaliwa kokutya okuqhelekileyo - umahluko oneziphumo zokwenyani zendlela ukutya okulawulwa ngayo.
Izinto ezibangela ukutya kwi-MCAS zihlala zimalunga nomxholo we-histamine kunye nokucaphuka kweeseli zemast kunokuba kukwaliwa kokutya okuqhelekileyo - umahluko oneziphumo zokwenyani zendlela ukutya okulawulwa ngayo.
Ihistamine iqokelelana ekutyeni njengoko iguga, ibila, okanye igcinwa. Ukutya okudala, okuphilisiwe, okubilisiweyo, okanye okushiywe efrijini iintsuku ezininzi kudla ngokuthwala ngaphezulu. Kungenxa yoko le nto ubutsha buhlala bubaluleke ngaphezu kwesithako esithile: intlanzi efanayo inokunyamezela kakuhle ngemini yokuthengwa kwayo kwaye inganyanyezelwa kakuhle kwiintsuku ezintathu kamva.
Iqela lesibini, ngamanye amaxesha libizwa ngokuba zii-histamine liberators, kukutya okubonakala kukhuthaza iiseli zemast ukuba zikhuphe ezazo i-histamine kunokuba zizihambise ngokwazo. Ingxenye yesithathu inegalelo ngotywala kunye nezongezo ezithile, ezinokuthi zongeze umthwalo kwaye ziphazamise i-enzymes ecacisa i-histamine.
Isilumkiso esibalulekileyo sesokuba ukutya okune-histamine esezantsi kuyathintelwa, kwaye ubungqina obupapashiweyo obuxhasayo bulinganiselwe kwaye bunomgangatho ophantsi. Uthintelo olwandisiweyo olungajongwanga lunomngcipheko wokwenyani wokunqongophala kwesondlo kunye nokutya okungalungelelananga, kwaye umngcipheko uphezulu kwabakwishumi elivisayo.Uninzi lweekliniki zincoma ixesha elilinganiselweyo, ulingo olucwangcisiweyo kunye nokuqaliswa kwakhona okucwangcisiweyo - kunye nokubandakanyeka kwe-dietitian apho umntu ekhoyo-kunokuphepha okuvulekileyo.
Ayizizo zonke iitrigger ezivela ngaphandle. Ezinye zezona zinamandla zivela kwimeko yangaphakathi yomzimba-eyinxalenye yesizathu sokuba i-MCAS inokuvutha ngexesha apho kungekho nto yangaphandle etshintshileyo.
Uxinzelelo sisiqhagamshelo somzimba, hayi isafobe. Iiseli zeMast zithwala i-receptors yehomoni ekhupha i-corticotropin kwaye zihlala kufutshane neziphelo zemithambo-luvo, zinika inkqubo ye-nervous indlela ethe ngqo yokuchaphazela ukusebenza kwayo. Le ndlela ifuna ugxininiso, kuba izigulane ezineempawu ezibuhlungu phantsi koxinzelelo zihlala zixelelwa ukuba imeko ngoko ingokwengqondo.Ingqikelelo ayilunganga: indlela ye-neuroimmune eboniswayo ayifani nophawu olucingelwayo.
Uxinzelelo sisiqhagamshelo somzimba, hayi isafobe. Iiseli zeMast zithwala i-receptors yehomoni ekhupha i-corticotropin kwaye zihlala kufutshane neziphelo zemithambo-luvo, zinika inkqubo ye-nervous indlela ethe ngqo yokuchaphazela ukusebenza kwayo. Le ndlela ifuna ugxininiso, kuba izigulane ezineempawu ezibuhlungu phantsi koxinzelelo zihlala zixelelwa ukuba imeko ngoko ingokwengqondo.Ingqikelelo ayilunganga: indlela ye-neuroimmune eboniswayo ayifani nophawu olucingelwayo.
Ukuguquguquka kweHormonal ixhaphakile ukuxelwa, ngakumbi malunga nokuya exesheni, kwaye ezinye izigulana zichaza utshintsho ngexesha lokukhulelwa okanye lokuyeka ukuya exesheni. I-Estrogen iphembelela ukuziphatha kweeseli zemast, eyingcaciso enye ecetywayo yokuba kutheni i-MCAS ifunyaniswa rhoqo kwabasetyhini.
Usulelo ngokuthembekileyo iphakamisa isiseko sokusebenza kwakhona. Izigulana ezininzi zifumanisa ukuba isigulo esiqhelekileyo sentsholongwane sikhulisa i-trigger yazo iiveki emva koko, kwaye izinto ebezinyanyezelwe ngaphambili ziye zixhokonxe ngexesha lokuchacha.
Amanye amachiza anokwenza ukuba i-mast cell isebenze ngokuthe ngqo. Le yenye yeendawo ezimbalwa apho ukuphambuka kunomngcipheko omkhulu, kwaye kufuneka kusingathwe noogqirha bakho.
Amanye amachiza anokwenza ukuba i-mast cell isebenze ngokuthe ngqo. Le yenye yeendawo ezimbalwa apho ukuphambuka kunomngcipheko omkhulu, kwaye kufuneka kusingathwe noogqirha bakho.
Iiklasi ezithile zamayeza zibonwa kuncwadi lweeseli zemast njengezinto ezinokuthi zisebenze. I-opioids, amayeza athile angeyo-steroidal achasene nokudumba, i-radiocontrast media, iziphumlisi zezihlunu ezisetyenziswa kwi-anesthesia, kunye ne-vancomycin zivela rhoqo. Ayizizo zonke izigulana ezisabela kuyo nayiphi na kwezi, kwaye abaninzi bazithatha ngaphandle kobunzima.
Izithako ezingasebenziyo zibalulekile. Idayi, izithinteli, kunye nezizalisi kwimixube zinokuba licandelo elixhokonxayo kunokuba libe lichiza elisebenzayo, kungoko isigulana sinokusabela kuguqulelo lwamayeza omenzi omnye kwaye sinyamezele omnye.
Utyando kunye ne-anesthesia ifanele ukucwangciswa kwangaphambili. Izigulane ezinokuxilongwa kwe-mast cell zicetyiswa ngokubanzi ukuba zazise amaqela otyando kunye ne-anesthetic ngaphambi komhla, ukwenzela ukuba i-agent inokukhethwa kunye nemeko engqondweni kunye nokuqwalaselwa kwangaphambili. Le yincoko ekufuneka iqalwe kwangethuba, hayi ekwamkelweni.
Ngenxa yokuba iiseti ze-trigger zizimele, ekuphela kwendlela ethembekileyo kukugcina irekhodi lomntu ngokucwangcisiweyo. Idayari yokuqalisa ayinamdla kwaye iyasebenza.
Ngenxa yokuba iiseti ze-trigger zizimele, ekuphela kwendlela ethembekileyo kukugcina irekhodi lomntu ngokucwangcisiweyo. Idayari yokuqalisa ayinamdla kwaye iyasebenza.
Rekhoda ngaphezu kokutya. Qaphela ixesha lemini, ubushushu be-ambient, into oyityileyo kunye nendlela entsha ngayo, umsebenzi womzimba, uxinzelelo kunye nokulala, ukuvezwa kwevumba, amayeza athathiweyo, kunye - kwizigulana ezihamba exesheni - isikhundla somjikelezo. Emva koko urekhode iimpawu kunye nexesha kunye nobukhulu bazo. Ingxaki yokusabela ngokulibaziseka ithetha ukuba sesichengeni sokuba imiba inokuhlala kwiiyure ezininzi phambi kophawu.
Iiveki ezimbini bubuncinane phambi kokuba iipateni zifundeke, kwaye zide zibengcono. Jonga uphinda-phindo kuzo zonke iziganeko kuneenkcazo zesiganeko esinye. Injongo yingcamango onokuyivavanya, hayi isigwebo.
Okokugqibela, gcina usukelo lusengqondweni. Injongo yokuchonga izinto ezibangela ukuba kuthotywe umthwalo opheleleyo owaneleyo wokwandisa ubomi bakho, hayi ukubucutha ubomi bakho de kube kungekho nto ixhokonxa ukusabela. Isithintelo esisusa yonke into oyixabisileyo ineendleko zayo ezinzulu - bona Unyango malunga nokuba unciphiso lwe-trigger luhambelana njani nolawulo lwezonyango.