Unyango malunga nokuba unciphiso lwe-trigger luhambelana njani nolawulo lwezonyango.">
Iikhrayitheriya zokuvumelana, iimvavanyo zomlamli kunye neemfuno zabo zokuphatha ezingqongqo, kutheni izinto ezingalunganga zixhaphakile, kunye nendlela yokulungiselela.

Ukuxilongwa kwe-MCAS | Iinkcukacha ze-MCAS

Izibonelelo - Ukuxilongwa

Ukufumana Ifunyenwe
Skrola
Ukuxilongwa kwe-MCAS kunzima ngesizathu esithile nesinokulungiswa: iimvavanyo zilinganisa iikhemikhali ezihlala ixesha elifutshane ekufuneka zibanjwe ngexesha lokusabela kwaye ziphathwe ngononophelo olungaqhelekanga.
Qalisa Ukufunda Ukufikelela kwiZibonelelo
0
indlela yokuvumelana ukuba
kufuneka zaneliseke zonke
0%
I-tryptase yonyuka ngaphezu kwesiseko
plus 2 ng/mL - umgubasi
0unyaka
0iiyure
window ukubamba i-trypase
emva kokuqalisa ukusabela

ixesha eliphakathi izigulane zilindile
ukuxilongwa ngokuchanekileyo

UMgangatho

AbaThathu Imigaqo yemvumelwano

Isakhelo esisetyenziswa ngokubanzi sifuna zonke iinkalo zontathu kunye. Intlanganiso enye okanye ezimbini azanelanga, kwaye kulapho uninzi lweworkups luzinzile.

Okokuqala, ipateni yeempawu. Iimpawu kufuneka ziphindaphindeke kwaye zibe yi-episodic, kwaye kufuneka zibandakanye iinkqubo zamalungu amabini okanye ngaphezulu. Iindibaniso eziqhelekileyo ziquka ulusu olunesisu, okanye i-cardiovascular with breathing. Ingxaki evaleleke kwisixokelelwano esinye, okanye enye ehlala ihleli endaweni yokuguquguquka, ayingeni.

Okwesibini, ubungqina obuyinjongo yokukhululwa kwe-mast cell mediator. Oku kuthetha umlinganiselo waselabhorethri - okuqhelekileyo ukunyuka kwe-serum tryptase ngexesha lesiqendu xa kuthelekiswa nesiseko esingenazo iimpawu zesigulana, okanye i-metabolites yomlamli ephakamileyo emchameni. I-tryptase threshold ekusetyenzisweni okuqhelekileyo kukunyuka okungenani kwe-20% ngaphezulu kwesiseko kunye ne-2 ng/mL eyongezelelweyo.

Okwesithathu, impendulo kunyango olujolise kwiiseli zemast. Ukuphuculwa kwe-H1 kunye ne-H2 i-antihistamines, i-mast cell stabilizers, okanye ii-arhente ezinxulumene nazo zixhasa ukuxilongwa. Lo mgaqo uthwala ubunzima bokwenyani ekusebenzeni, ngakumbi apho uvavanyo lomlamli lungakhange lubekho.

Ecaleni kwezi, ezinye iimeko ezikwaziyo ukuvelisa umfanekiso ofanayo kufuneka zingabandakanywa - kubandakanywa i-mastocytosis, ebandakanya ukugqithisa okwenyani kweeseli zemast kwaye iphandwa ngokwahlukileyo. Qaphela ukuba iinguqu zesi sikhokelo zikhona kwaye iingcali ziyahluka ngendlela engqongqo ngayo ikhrayitheriya yesibini; Indlela kagqirha inokwahluka ngokufanelekileyo kule ichazwe apha.

Zontathu iikhrayitheriya, kunye. Owesibini - ubungqina obunenjongo - kulapho uninzi lweehambo zokuxilonga zihlala khona, kwaye ngokuqhelekileyo ngenxa yezizathu zobugcisa kunokuba isigulane singenayo imeko.

Uvavanyo

Iimvavanyo Ibandakanyiwe

ISerum tryptase sesona siphawuli sisekiweyo. Ifuna imilinganiselo emibini ukuze itolike: omnye uthathwe ngexesha okanye kamsinya nje emva kokusabela, kwaye omnye uthathwe kwisiseko xa iimpawu zizolile. Ixabiso elinye elahlukileyo kunzima ukwenza kulo, kuba okubalulekileyo lutshintsho olusuka kwisiseko somntu kunokuba inani elipheleleyo.Isampulu ebukhali kufuneka izotywe kwisithuba esimalunga neyure enye ukuya kwezine yokusabela kokuqala, kunye nesampulu esisiseko ubuncinci iiyure ezingama-24 emva kokuba iimpawu zizinzile.

Iingqokelela zomchamo weeyure ezingama-24 ukulinganisa i-metabolites yomlamli - ngokuqhelekileyo i-N-methylhistamine, i-prostaglandin D2 okanye i-metabolite yayo ye-11-beta-prostaglandin F2-alpha, kunye ne-leukotriene E4. Ezi zibamba ifestile ende kunotsalo lwegazi elinye kwaye ziyakwazi ukubona ukwenzeka okunokuthi kuphoswe sisnapshot. Kufanele ukuba ziqaliswe ngexesha leempawu.

Iimfuno zokuphatha zingqongqo, kwaye zezona zizathu zixhaphakileyo iziphumo zibuya zingalunganga ngobuxoki. Iqela laba balamli alizinzanga kubushushu begumbi. Iisampulu zidla ngokufuna ukugodoliswa ngoko nangoko, zigcinwe zibanda ngexesha lonke lokuqokelelwa, kwaye zilungiswe ngokukhawuleza. Iisampuli zeProstaglandin zibuthathaka ngakumbi. Umzekelo oshiywe kwikhawuntara, okanye othunyelwe ngezothutho eziqhelekileyo, unokuvelisa umphumo oqhelekileyo kwisigulane ebesisabela ngokunyanisekileyo.

Ngenxa yoko, kuyafaneleka ukuba uqinisekise iprotocol yokuphatha kunye nogqirha oyalelayo kunye nebhubhoratri ngaphambili ingqokelela kunokuba emva kwesiphumo esingalindelekanga. Ayizizo zonke iilebhu ngokubanzi eziqhuba ezi mvavanyo, kwaye ayizizo zonke izixhobo zokuqokelela ezifika zinemiyalelo eyaneleyo.

Ngaphambi kokuba Uvavanye

  • Yintoni Ejongela Phantsi
    Isiphumo Esisebenzayo
  • Uninzi lwezinto ezingalunganga ezingalunganga kuvavanyo lwe-MCAS zezobuchwephesha kunezebhayoloji. La ngamanqaku okusilela afanele ukujongwa kwangaphambili.
  • Isampuli ngaphandle kwempendulo - Amanqanaba omlamli anokuba yinto eqhelekileyo phakathi kweziqephu
  • Ilahlekile ifestile ebukhali I-tryptase idla ngokutsalwa kwiiyure ezi-1-4 emva kokuba iqalile
  • Akukho luthelekiso lwesiseko - ixabiso elinye alikwazi ukubonisa ukunyuka
  • Ukuphatha ngokufudumeleyo - abalamli abaninzi bathoba kwiqondo lokushisa
  • Ukuqhubekeka kulibazisekile - ixesha lokuthutha lilodwa linokwenza umphumo ube yinto eqhelekileyo
I-Antihistamines ayichazwanga -xoxa ngexesha kunye nogqirha wakho - ungayeki ucalanye

Ukungaziwa kweLebhu - ayizizo zonke iilebhu eziqhuba olu vavanyo rhoqo

Ukutolikwa

I-Medical Disclaimer: Eli phepha liyafundisa kwaye alilona cebiso lonyango. I-MCAS iveza ngokwahlukileyo kwisigulana ngasinye - soloko usebenza nababoneleli bezempilo abaqeqeshiweyo abayaziyo imbali yakho ngaphambi kokuba benze nantoni na oyifundayo apha.

Kutheni Ziza Iziphumo
Emva Okuqhelekileyo

Uvavanyo lomlamli ongalunganga aluyikhupheli ngaphandle i-MCAS - kunye nokuqonda ukuba kutheni kuthintela ukudimazeka okukhulu okungeyomfuneko.

Iimvavanyo zilinganisa iikhemikhali ezinobomi obufutshane obufutshane. Incopho ye-Trypase kwiiyure ezimbalwa zokusabela ize iwe; I-metabolites yomchamo ihlala ixesha elide kodwa ibonakalisa ifestile elinganiselweyo. Ukuba isampulu ithathwa phakathi kweziqendu, kusenokungabikho nto iphakanyisiweyo ukuba ifunyanwe - hayi ngenxa yokuba ukusebenza akuzange kwenzeke, kodwa ngenxa yokuba akusalinganiseki.

Iingxaki zokuphatha ezichazwe ngasentla zidibanisa oku. Phakathi kwengqokelela engafanelekanga kunye neesampulu ezithotyiweyo, isabelo esikhulu seziphumo ezibi kuncwadi kunye neeakhawunti zesigulana kukungaphumeleli kobugcisa kunokungabikho kokwenyani kwesifo.

Eli phepha alinakukuxelela ukuba ngawaphi amayeza akhuselekileyo kuwe. Musa ukuyeka, ukuphepha, okanye ukuguqula iyeza elimiselweyo ngokwesiseko soluhlu oluqhelekileyo - yizisa uluhlu kugqirha owaziyo imbali yakho kwaye wenze isigqibo kunye. Umngcipheko wokuyeka unyango olufunekayo yinyani, kwaye kwezinye iimeko mkhulu kunomngcipheko ophetshwayo.

Kukho umda ongaphaya: iipaneli ezisemgangathweni zilinganisa inani elincinci labalamli, ngelixa iiseli zemast zikhulula amakhulu. Isigulane esinokusebenza kulawulwa ngabalamli abangabandakanywanga ngovavanyo lwesiqhelo banokusabela ngokunyanisekileyo kwaye bavavanye ngokuqhelekileyo kulo lonke.

Akukho nanye kwezi kuthetha ukuba uvavanyo kufuneka lutsibe. Ubungqina benjongo bomeleza uxilongo kakhulu, luvula ufikelelo kunyango, kunye nemiba ye-inshurensi kunye neendawo zokuhlala. Kuthetha ukuba umphumo oqhelekileyo kufuneka uqhube incoko malunga nexesha kunye nokusingatha - kwaye mhlawumbi umzamo wokuphinda ngexesha lokuphendula - kunokuba uvale umbuzo.

Ukulungiselela
i Ukuqeshwa

Ukulibaziseka koxilongo kwi-MCAS kuyinxalenye yesakhiwo - iimpawu ziwela imigca ekhethekileyo, kwaye ingcali nganye ibona ummandla omnye wengxaki yenkqubo. Ukufika nomfanekiso uphela osele udityanisiwe yeyona nto iluncedo kakhulu enokwenziwa sisigulana.

Yiza nembali yeempawu ezibhaliweyo ezicwangcisiweyo ngenkqubo yamalungu kunokuba ngokolandelelwano lwamaxesha. Uluhlu lwesikhumba, i-gastrointestinal, i-cardiovascular, i-respiratory, kunye neempawu ze-neurological njengamaqela enza ipateni ye-multisystem ibonakale ngokukhawuleza, apho i-akhawunti ebalisayo idla ngokuyifihla.

Yiza nedayari yakho yokuqalisa ukuba uyigcinile-bona Izichukumisi ukwenzela ukuba urekhode ntoni. Iziqendu ezibhaliweyo ezinexesha kunye nobungqongqo zinika ugqirha into ebambekayo anokuthi asebenze kuyo, kwaye ancede ekusekeni ipateni ye-episodic efunwa yikhrayitheriya yokuqala.

Yiza neziphumo zovavanyo lwangaphambili, kuquka nezingenayo. Iiphaneli eziqhelekileyo zokungalungi, ii-endoscopies ezingenakulinganiswa, kunye nokusebenza okucacileyo kwentliziyo zinolwazi: ziyingxenye yenkqubo yokukhutshwa, kwaye zisindisa ukuphindaphinda iimvavanyo esele zenziwe.

Awungo Wedwa

Iinkcukacha ze-MCAS zikhona ukuze kuqinisekiswe ukuba isigulana ngasinye siyafikelela kwinkxaso, kuluntu, kunye nolwazi lokuzithethelela. Joyina inethiwekhi yethu yehlabathi.

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