Ukwelashwa ukuthi ukuncipha kwe-trigger kufanelana kanjani nokuphathwa kwezokwelapha.">
Imibandela yokuvumelana, izivivinyo zomlamuleli kanye nezidingo zabo eziqinile zokuphatha, kungani ama-negative angamanga avamile, kanye nendlela yokulungiselela.

Ukuxilongwa kwe-MCAS | Imininingwane ye-MCAS

Izinsiza - Ukuxilongwa

Ukuthola Kuxilongwa
Skrola
Ukuxilongwa kwe-MCAS kunzima ngesizathu esithile nesilungisekayo: ukuhlola kukala amakhemikhali esikhashana okufanele abanjwe ngesikhathi sokusabela futhi asingathwe ngokunakekelwa okungajwayelekile.
Qala Ukufunda Finyelela Izinsiza
0
imigomo yokuvumelana ukuthi
kumele wonke aneliseke
0%
I-tryptase ikhuphuka ngaphezu kwesisekelo
plus 2 ng/mL - umkhawulo
0unyaka
0amahora
iwindi lokuthwebula i-tryptase
ngemva kokuqala kokusabela

isilinganiso sesikhathi iziguli ezilindile
ukuze uthole ukuxilongwa okunembile

Izinga

AbaThathu Imibandela Yokuvumelana

Uhlaka olusetshenziswa kabanzi ludinga zonke izakhi ezintathu ndawonye. Ukuhlangana nokukodwa noma okubili akwanele, futhi kulapho ama-workups amaningi agcina khona.

Okokuqala, iphethini yezimpawu. Izimpawu kufanele ziphindaphindeke futhi zibe yi-episodic, futhi kufanele zibandakanye amasistimu wezitho ezimbili noma ngaphezulu. Izinhlanganisela ezijwayelekile zihlanganisa isikhumba esinamathumbu, noma inhliziyo nemithambo yokuphefumula. Inkinga evalelwe ohlelweni olulodwa, noma leyo engaguquki kunokuguquguquka, ayilingani.

Okwesibili, ubufakazi obuhlosiwe bokukhululwa komlamuleli we-mast cell. Lokhu kusho isilinganiso seselabhorethri - ngokuvamile ukwenyuka kwe-serum tryptase phakathi nesiqephu uma kuqhathaniswa nesisekelo esingenazimpawu zesiguli, noma ama-metabolite aphakeme angumlamuli emchameni. Umkhawulo we-tryptase osetshenziswa okuvamile uwukukhuphuka okungenani okungu-20% ngaphezu kwesisekelo kanye no-2 ng/mL eyengeziwe.

Okwesithathu, impendulo yokwelashwa eqondiswe kuma-mast cells. Ukuthuthukiswa kwama-antihistamine e-H1 ne-H2, iziqinisi zeseli ye-mast, noma ama-ejenti ahlobene asekela ukuxilongwa. Lo mbandela unesisindo sangempela ekusebenzeni, ikakhulukazi lapho ukuhlolwa komlamuli bekungahlangani.

Eceleni kwalokhu, ezinye izimo ezikwazi ukukhiqiza isithombe esifanayo kufanele zingafakwa - okuhlanganisa i-mastocytosis, ehilela ukweqisa kwangempela kwamaseli ensika futhi iphenywa ngendlela ehlukile. Qaphela ukuthi ukuhlukahluka kwalolu hlaka kukhona futhi ochwepheshe bayehluka ngokuthi bawusebenzisa ngokuqinile kanjani umbandela wesibili; indlela kadokotela ingase yehluke ngokunengqondo kulokho okuchazwe lapha.

Zontathu izindlela, ndawonye. Owesibili - ubufakazi obuhlosiwe - yilapho uhambo oluningi lokuxilonga luhlala khona, futhi ngokuvamile ngenxa yezizathu zobuchwepheshe kunokuba ngoba isiguli asinaso isimo.

Ukuhlola

Izivivinyo Kubandakanyekile

I-serum tryptase umaka osungulwe kakhulu. Kudinga izilinganiso ezimbili ukuze zichazeke: esisodwa esithathwe ngesikhathi noma ngokushesha ngemva kokusabela, futhi esisodwa esithathwe ekuqaleni lapho izimpawu zithulile. Inani elilodwa elihlukanisiwe kunzima ukwenza ngalo, ngoba okubalulekile wushintsho olusuka kusisekelo somuntu esikhundleni senombolo ephelele. Isampula ebukhali kufanele zidwetshwe cishe phakathi nehora elilodwa kuya kwamane kusukela kuqale ukusabela, kanye nesampula eyisisekelo okungenani emahoreni angama-24 ngemva kokuqeda izimpawu.

Ukuqoqwa komchamo wamahora angu-24 linganisa ama-metabolites omlamuli - ngokuvamile i-N-methylhistamine, i-prostaglandin D2 noma i-metabolite yayo engu-11-beta-prostaglandin F2-alpha, ne-leukotriene E4. Lokhu kuthwebula iwindi elide kunokudonsa igazi okukodwa futhi kungathola ukwenziwa kusebenze okungaphuthelwa yisithombe esifushane. Kufanele ziqalwe ngesikhathi esinezimpawu.

Izidingo zokuphatha ziqinile, futhi ziyisizathu esivame kakhulu ukuthi imiphumela ibuye ingelona iqiniso. Abaningana balaba balamuli abazinzile ezingeni lokushisa legumbi. Amasampuli ngokuvamile adinga ukupholiswa ngokushesha, agcinwe ebanda ngesikhathi eqoqwa, futhi acutshungulwe ngokushesha. Amasampula e-Prostaglandin antekenteke kakhulu. Isifanekiso esishiywe kukhawunta, noma esithunyelwe izinto zokuhamba ezijwayelekile, singaveza umphumela ojwayelekile ovela esigulini ebesisabela ngokweqiniso.

Ngenxa yalokhu, kufanelekile ukuqinisekisa iphrothokholi yokuphatha nodokotela o-oda kanye nelabhorethri ngaphambili iqoqo kunokuba ngemva komphumela ongalindelekile. Akuwona wonke amalabhorethri ajwayelekile asebenzisa lezi zivivinyo, futhi akuwona wonke amakhithi eqoqo afika anemiyalelo eyanele.

Ngaphambi Kokuhlola

  • Yini Elulaza
    Umphumela Ovumelekile
  • Iningi lezinto ezingezinhle ezingamanga ekuhlolweni kwe-MCAS zingokobuchwepheshe kunezemvelo. Lawa amaphuzu okuhluleka okufanele uwahlole kusengaphambili.
  • Isampula ngaphandle kokusabela - Amazinga womlamuli angaba ajwayelekile phakathi kweziqephu
  • Iwindi elibukhali alikho I-tryptase ivame ukudonswa emahoreni angu-1-4 ngemva kokuqala
  • Akukho ukuqhathanisa kwesisekelo — inani elilodwa alikwazi ukukhombisa ukuphakama
  • Ukubamba okufudumele - abalamuli abaningana behlisa izinga lokushisa ekamelweni
  • Ukucubungula okubambezelekile - isikhathi sokuthutha sisodwa singenza umphumela ube ojwayelekile
Ama-Antihistamine awabalwa - xoxa nesikhathi nodokotela wakho - ungayeki uhlangothi olulodwa

Ukungajwayelekile elabhorethri - akuwona wonke amalebhu asebenzisa lezi zivivinyo njalo

Ukutolika

Umshwana wokuzikhipha emthwalweni wezempilo: Leli khasi liyafundisa futhi alisona iseluleko sezokwelapha. I-MCAS yethula ngendlela ehlukile kuso sonke isiguli - hlala usebenza nabahlinzeki bezempilo abaqeqeshiwe abawazi umlando wakho ngaphambi kokuthatha isinyathelo kunoma yini oyifunda lapha.

Kungani Kufika Imiphumela
Emuva Okuvamile

Ukuhlolwa komlamuleli ongemuhle akukhiphi i-MCAS ngokwayo - nokuqonda ukuthi kungani kuvimbela ukudumazeka okuningi okungadingekile.

Ukuhlola kukala amakhemikhali anesigamu sokuphila esifushane. I-Tryptase ifinyelela isiqongo phakathi namahora ambalwa okusabela bese iwe; ama-metabolites omchamo aphikelela isikhathi eside kodwa asabonisa iwindi elilinganiselwe. Uma isampuli ithathwa phakathi kweziqephu, kungase kungabi khona lutho oluphakeme olungatholwa - hhayi ngoba ukuqalisa akukaze kwenzeke, kodwa ngoba akusalinganiseki.

Izinkinga zokusingatha ezichazwe ngenhla zihlanganisa lokhu. Phakathi kokuqoqwa kwesikhathi esingafanele namasampuli awonakele, ingxenye enkulu yemiphumela engemihle ezincwadini nasema-akhawuntini esiguli ukwehluleka kwezobuchwepheshe kunokungabikho kwesifo kwangempela.

Leli khasi alikwazi ukukutshela ukuthi yimiphi imithi ephephile kuwe. Ungayeki, ugweme, noma uguqule umuthi owunikeziwe ngesisekelo sohlu olujwayelekile - letha uhlu kudokotela owazi umlando wakho futhi ninqume ndawonye. Ingozi yokuyeka ukwelashwa okudingekayo ingokoqobo, futhi kwezinye izimo inkulu kunengozi egwenywayo.

Kukhona omunye umkhawulo: amaphaneli ajwayelekile akala inani elincane labalamuli, kuyilapho amaseli e-mast ekhulula amakhulu. Isiguli ukusebenza kwaso kubuswa abalamuli abangafakwanga ukuhlolwa okujwayelekile singasabela ngokweqiniso futhi sihlole ngokujwayelekile kulo lonke.

Akukho kulokhu okusho ukuthi ukuhlolwa kufanele kweqiwe. Ubufakazi obuhlosiwe buqinisa ukuxilongwa kakhulu, buvula ukufinyelela ekwelashweni, kanye nezindaba zomshwalense kanye nezindawo zokuhlala. Kusho ukuthi umphumela ojwayelekile kufanele udale ingxoxo mayelana nesikhathi nokusingatha - futhi mhlawumbe umzamo wokuphinda ngesikhathi sokusabela - kunokuvala umbuzo.

Ukulungiselela
i Ukuqokwa

Ukulibaziseka kokuxilonga ku-MCAS kuyingxenye yesakhiwo - izimpawu zeqa imigqa ekhethekile, futhi uchwepheshe ngamunye ubona isifunda esisodwa senkinga yesistimu. Ukufika nesithombe sonke esivele siqoqiwe yinto eyodwa ewusizo kakhulu isiguli esingayenza.

Letha umlando wezimpawu obhaliwe ohleliwe ngohlelo lwesitho esikhundleni sokulandelana kwezenzakalo. Ukufaka kuhlu isikhumba, amathumbu, inhliziyo nemithambo yegazi, izimpawu zokuphefumula, kanye nezimpawu zemizwa njengamaqembu kwenza iphethini ye-multisystem ibonakale ngokushesha, lapho i-akhawunti elandisayo ivame ukuyifihla.

Letha idayari yakho yokuqalisa uma uyigcinile - bheka Izicupha lokho ongakuqopha. Iziqephu ezibhalwe phansi ezinesikhathi nobulukhuni zinikeza umtholampilo okuthile okuphathekayo angasebenza ngakho, futhi zisize ukusungula iphethini yesiqephu esidingwa umbandela wokuqala.

Letha imiphumela yokuhlolwa kwangaphambilini, okuhlanganisa nethi negative. Amaphaneli ajwayelekile okungezwani komzimba nezinto ezithile, ama-endoscopies angaphawuleki, kanye nokusebenza okucacile kwenhliziyo kuyafundisa: ayingxenye yenqubo yokukhishwa, futhi asindisa ukuphindaphindwa kokuhlolwa osekwenziwe.

Awuyena Ngedwa

Imininingwane ye-MCAS ikhona ukuze kuqinisekiswe ukuthi sonke isiguli siyakwazi ukuthola ukwesekwa, umphakathi, kanye nolwazi lokuzikhulumela. Joyina inethiwekhi yethu yomhlaba wonke.

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